Saltatory waves in the spike-diffuse-spike model of active dendritic spines.

نویسندگان

  • S Coombes
  • P C Bressloff
چکیده

In this Letter we present the explicit construction of a saltatory traveling pulse of nonconstant profile in an idealized model of dendritic tissue. Excitable dendritic spine clusters, modeled with integrate-and-fire (IF) units, are connected to a passive dendritic cable at a discrete set of points. The saltatory nature of the wave is directly attributed to the breaking of translation symmetry in the cable. The conditions for propagation failure are presented as a function of cluster separation and IF threshold.

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Saltatory waves in the spike-di use-spike model of active dendritic spines

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عنوان ژورنال:
  • Physical review letters

دوره 91 2  شماره 

صفحات  -

تاریخ انتشار 2003